The PharmaJet needle-free system expels liquid at high speed, creating a “liquid jet” that penetrates the skin and delivers the intended liquid in less than a third of a second—faster than the body’s nervous system can react. While experiences range, some people experience no sensation and others some mild discomfort. Studies to date, however, show predominant preference for needle free injection, versus needle and syringe.

The technology has been engineered to enable consistent delivery into the three different depths of tissue that might be prescribed for injection—intra-dermal (ID), subcutaneous (SC), and intra-muscular (IM). While SC and IM depths are most commonly used, intra-dermal delivery (particularly for vaccines) is perhaps the most exciting for both manufacturers and health care policymakers. In animal models, PharmaJet’s studies have shown that 20% of the standard dose of a vaccine—delivered into the skin (or intra-dermal) — elicits the same or better immune response than a full dose delivered into the subcutaneous or muscular areas of the body. Scientists believe that by delivering vaccine into the dermal layer, the immune response is boosted due to increased dendritic cell exposure. Significant testing continues to advance for intra-dermal delivery, with certain vaccine manufacturers highly interested in what the dose-sparing potential may create for their competitive advantage—and certain governments highly interested in what it may mean for reducing their healthcare expenditures.

For manufacturers of vaccines, ID delivery could result in considerable manufacturing and distribution cost savings. For vaccines in short supply, more people might be able to be vaccinated. For governments and insurers who help pay for the vaccines, savings might be redirected to provide for vaccination of more people, or for more and different kinds of vaccines to be made available. Added to this, because PharmaJet’s syringe has no needle, there is reduced disposal burden and costs. Ultimately, the inter-relationship of all these factors makes healthcare more cost-effective—and a step closer toward the PharmaJet goal of helping reduce the disease burden costs the world shares.

Below are other key advantages of the PharmaJet system:

No Needle, No Fear

The PharmaJet syringe contains no needle; and its auto-disable feature makes it impossible to re-use. This eliminates two of the greatest concerns in health care: Needle stick injury to health care givers, and cross contamination caused by re-use of needles.

Less Distress

PharmaJet’s speed of injection is faster than the body can register the sensation. Less painful and less stressful injections may help increase patient compliance, making individuals healthier, and reducing the global disease burden.

Less Expensive by Design

The PharmaJet system is different from needle and syringe systems, but also different from other needle-free systems. Our patented needle-free injector system uses a syringe made from polypropylene – the same material used in standard needle syringes – which is less than half as expensive as the polycarbonate materials used by most other needle-free producers. The resulting product not only costs less, but is also well-suited for field-filling or for pre-filling – which could also make the system a combination drug storage and delivery device, simultaneously saving time and money.

User Friendly

The PharmaJet system is suitable for use on people of all ages and skin types. It requires no outside power source. It’s easy to teach users or health-care givers everywhere to use.

Waste Not

The syringe has a verifiably accurate fixed dose system, providing for efficient injection and reducing drug wastage. Further, the polypropylene used to make the syringe could be recycled (with proper handling).

Auto-Disable

Once used, the PharmaJet syringe is auto-disabled. Unlike other needle free injectors that are able to be re-used multiple times—which could be useful for the home environment — PharmaJet’s syringe eliminates the possibility that syringes will be recovered from garbage dumps, which is sadly common in some countries, and reused or repackaged and sold again.

Revolutionary Potential

On a per-patient basis, the PharmaJet system’s cost of delivery and disposal is cost-competitive with auto-destruct and safety needle syringes. As effective as vaccination by traditional needle syringe — and likely more so — reduction in pain, anxiety, sharps disposal costs, and materials provide for PharmaJet to make a revolutionary and positive difference to vaccine delivery around the world, in any environment or setting.